MSH6 monoclonal antibody, clone SP93
产品名称: MSH6 monoclonal antibody, clone SP93
英文名称: MSH6 monoclonal antibody, clone SP93
产品编号: MAB10045
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit monoclonal antibody raised against synthetic peptide of MSH6.
- Immunogen:
- A synthetic peptide corresponding to internal region of human MSH6.
- Host:
- Rabbit
- Theoretical MW (kDa):
- 170
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Affinity purification
- Storage Buffer:
- In 10 mM PBS, pH 7.4 (BSA, sodium azide)
- Storage Instruction:
- Store at 4°C. Do not freeze.
- Recommend Usage:
- Western Blot (1:100)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:100)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Entrez GeneID:
- 2956
- Gene Name:
- MSH6
- Gene Alias:
- GTBP,HNPCC5,HSAP
- Gene Description:
- mutS homolog 6 (E. coli)
- Omim ID:
- 600678
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a protein similar to the MutS protein. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides, prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein of this gene combines with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene have been identified in individuals with hereditary nonpolyposis colon cancer (HNPCC) and endometrial cancer. [provided by RefSeq
- Other Designations:
- G/T mismatch-binding protein,mutS homolog 6,sperm-associated protein
- Gene Pathway
- Related Disease
- Adenocarcinoma
- Adenoma
- Adenomatous Polyposis Coli
- Anticipation, Genetic
- Ataxia telangiectasia
- Breast cancer
- Breast Neoplasms
- Carcinoma
- Carcinoma, Papillary
- Chromosomal Instability
- Colon cancer
- Colonic Neoplasms
- Colonic Polyps
- Colorectal Neoplasms
- Colorectal Neoplasms, Hereditary Nonpolyposis
- Cystadenocarcinoma, Serous
- Disease Progression
- Duodenal Neoplasms
- Endometrial Neoplasms