Recombinant Human Interleukin-31
产品名称: Recombinant Human Interleukin-31
英文名称:
产品编号: 101-31
产品价格: 0
产品产地: 上海
品牌商标: 普欣
更新时间: null
使用范围: null
上海普欣生物技术有限公司
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- 地址 : 邯郸路100号
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- 所在区域 : 上海
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- 邮箱 : info@primegene.com.cn
Human IL-31 gene is located on Chr.12. It expresses the IL-31 protein at low levels in the type 2 helper T cells, which exits in testis, bone marrow, skeletal muscle, kidney, colon, thymus, small intestine and trachea. This protein shares several structural and functional characteristics with IL-6, Oncostatin M, LIF, and Cardiotrophin-1. IL-31 signals through IL-31 receptor A and oncostatin M receptor subunits and can activate STAT3 through receptors and maybe involve in skin immunity. It regulated immune responses have been implicated in skin physiology and inflammatory skin diseases. Human IL-31 shares 24 % a.a. sequence identity in the mature protein with mouse IL-31.