产品概述：Purified recombinant protein of Human insulin-like growth factor 1 receptor (IGF1R), with C-terminal DDK/His tag, expressed in human cells

蛋白长度：A DNA sequence from GoldORF clone, [GH68997V], encoding the extracellular domain (Asp741-His935) of human PDGFRB

表达系统：HEK293

种属：Human

标签类型：C-DDK/His

分子量：25 kDa

通用名：IGF1R

总结：This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]

形式：Liquid

浓度：>50 ug/mL as determined by microplate BCA method

纯度：> 80% as determined by SDS-PAGE and Coomassie blue staining

储存溶液：PBS, pH7.4, 10% glycerol

别名：CD221; IGFIR; IGFR; JTK13