SLC33A1 monoclonal antibody (M07), clone 3A4
产品名称： SLC33A1 monoclonal antibody (M07), clone 3A4
英文名称： SLC33A1 monoclonal antibody (M07), clone 3A4
产品编号： H00009197-M07
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a partial recombinant SLC33A1.
- Immunogen:
- SLC33A1 (NP_004724, 1 a.a. ~ 69 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- MSPTISHKDSSRQRRPGNFSHSLDMKSGPLPPGGWDDSHLDSAGREGDREALLGDTGTGDFLKAPQSFR
- Host:
- Mouse
- Reactivity:
- Human, Rat
- Isotype:
- IgG2a Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (33.33 KDa) .
- MSDS:
Download
- Publication Reference
- 1.
- SLC33A1/AT-1 regulates the induction of autophagy down-stream of IRE1/XBP1.
Pehar M, Jonas MC, Hare TM, Puglielli L.J Biol Chem. 2012 Jul 11.
- 2.
- AT-1 is the ER membrane acetyl-CoA transporter and is essential for cell viability.
Jonas MC, Pehar M, Puglielli L.J Cell Sci. 2010 Oct 1;123(Pt 19):3378-88. Epub 2010 Sep 7.
- Applications
- Western Blot (Cell lysate)
- SLC33A1 monoclonal antibody (M07), clone 3A4 Western Blot analysis of SLC33A1 expression in PC-12 ( Cat # L012V1 ).
- Protocol Download
- Western Blot (Transfected lysate)
- Western Blot analysis of SLC33A1 expression in transfected 293T cell line by SLC33A1 monoclonal antibody (M07), clone 3A4.
Lane 1: SLC33A1 transfected lysate(60.9 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Western Blot (Recombinant protein)
- Protocol Download
- Sandwich ELISA (Recombinant protein)
- Detection limit for recombinant GST tagged SLC33A1 is 0.03 ng/ml as a capture antibody.
- Protocol Download
- RNAi Knockdown (Antibody validated)
- Western blot analysis of SLC33A1 over-expressed 293 cell line, cotransfected with SLC33A1 Validated Chimera RNAi ( Cat # H00009197-R01V ) (Lane 2) or non-transfected control (Lane 1). Blot probed with SLC33A1 monoclonal antibody (M07), clone 3A4 (Cat # H00009197-M07 ). GAPDH ( 36.1 kDa ) used as specificity and loading control.
- Protocol Download
- Entrez GeneID:
- 9197
- GeneBank Accession#:
- NM_004733
- Protein Accession#:
- NP_004724
- Gene Name:
- SLC33A1
- Gene Alias:
- ACATN,AT-1,AT1,SPG42
- Gene Description:
- solute carrier family 33 (acetyl-CoA transporter), member 1
- Omim ID:
- 603690
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The encoded protein is required for the formation of O-acetylated (Ac) gangliosides. It is predicted to contain 6 to 10 transmembrane domains, and a leucine zipper motif in transmembrane domain III. Studies indicate that the protein is localized to the cytoplasm. [provided by RefSeq
- Other Designations:
- acetyl-Coenzyme A transporter,acetyl-coenzyme A transporter,spastic paraplegia 42 (autosomal dominant)
- Related Disease