产品概述：Purified recombinant protein of Human transmembrane protein 100 (TMEM100), transcript variant 2, full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug

蛋白长度：A DNA sequence encoding human full-length TMEM100

表达系统：E. coli

种属：Human

标签类型：N-GST and C-His

分子量：42.2 kDa

通用名：TMEM100

总结：Plays a role during embryonic arterial endothelium differentiation and vascular morphogenesis through the ACVRL1 receptor-dependent signaling pathway upon stimulation by bone morphogenetic proteins, such as GDF2/BMP9 and BMP10. Involved in the regulation of nociception, acting as a modulator of the interaction between TRPA1 and TRPV1, two molecular sensors and mediators of pain signals in dorsal root ganglia (DRG) neurons. Mechanistically, it weakens their interaction, thereby releasing the inhibition of TRPA1 by TRPV1 and increasing the single-channel open probability of the TRPA1-TRPV1 complex.[UniProtKB/Swiss-Prot Function]

形式：Liquid

浓度：>50 ug/mL as determined by microplate BCA method

纯度：> 80% as determined by SDS-PAGE and Coomassie blue staining

储存溶液：50mM Tris, pH8.0, 8M Urea.

别名：FLJ10970; FLJ37856