产品概述：Purified recombinant protein of Human S-phase kinase-associated protein 1 (SKP1), transcript variant 1, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug

蛋白长度：A DNA sequence encoding human full-length SKP1

表达系统：E. coli

种属：Human

标签类型：N-His

分子量：17.9 kDa

通用名：SKP1

总结：This gene encodes a component of SCF complexes, which are composed of this protein, cullin 1, a ring-box protein, and one member of the F-box family of proteins. This protein binds directly to the F-box motif found in F-box proteins. SCF complexes are involved in the regulated ubiquitination of specific protein substrates, which targets them for degradation by the proteosome. Specific F-box proteins recognize different target protein(s), and many specific SCF substrates have been identified including regulators of cell cycle progression and development. Studies have also characterized the protein as an RNA polymerase II elongation factor. Alternative splicing of this gene results in two transcript variants. A related pseudogene has been identified on chromosome 7. [provided by RefSeq, Jul 2008]

形式：Liquid

浓度：>50 ug/mL as determined by microplate BCA method

纯度：> 80% as determined by SDS-PAGE and Coomassie blue staining

储存溶液：50mM Tris, 8M Urea, pH8.0.

别名：EMC19; OCP-II; OCP2; p19A; SKP1A; TCEB1L