NPHS1 Rabbit pAb (APR25091N)
产品名称: NPHS1 Rabbit pAb (APR25091N)
英文名称: NPHS1 Rabbit pAb (APR25091N)
产品编号: APR25091N
产品价格: null
产品产地: 美国
品牌商标: Leading Biology
更新时间: null
使用范围: ELISA (Mus musculus)
安诺伦(北京)生物科技有限公司
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分子量:Calculated MW: 130kDa/134kDa Observed MW: 130kDa 细胞定位:Cell membrane, Single-pass type I membrane protein 稀释方法:WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:50 - 1:200 总结:This gene encodes a member of the immunoglobulin family of cell adhesion molecules that functions in the glomerular filtration barrier in the kidney. The gene is primarily expressed in renal tissues, and the protein is a type-1 transmembrane protein found at the slit diaphragm of glomerular podocytes. The slit diaphragm is thought to function as an ultrafilter to exclude albumin and other plasma macromolecules in the formation of urine. Mutations in this gene result in Finnish-type congenital nephrosis 1, characterized by severe proteinuria and loss of the slit diaphragm and foot processes.