NPHS1 Rabbit pAb (APR25091N)-抗体-抗体-生物在线
安诺伦(北京)生物科技有限公司
NPHS1 Rabbit pAb (APR25091N)

NPHS1 Rabbit pAb (APR25091N)

商家询价

产品名称: NPHS1 Rabbit pAb (APR25091N)

英文名称: NPHS1 Rabbit pAb (APR25091N)

产品编号: APR25091N

产品价格: null

产品产地: 美国

品牌商标: Leading Biology

更新时间: null

使用范围: ELISA (Mus musculus)

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分子量:Calculated MW: 130kDa/134kDa
Observed MW: 130kDa

细胞定位:Cell membrane, Single-pass type I membrane protein

稀释方法:WB 1:500 - 1:2000
IHC 1:50 - 1:100
IF 1:50 - 1:200

总结:This gene encodes a member of the immunoglobulin family of cell adhesion molecules that functions in the glomerular filtration barrier in the kidney. The gene is primarily expressed in renal tissues, and the protein is a type-1 transmembrane protein found at the slit diaphragm of glomerular podocytes. The slit diaphragm is thought to function as an ultrafilter to exclude albumin and other plasma macromolecules in the formation of urine. Mutations in this gene result in Finnish-type congenital nephrosis 1, characterized by severe proteinuria and loss of the slit diaphragm and foot processes.