ADK polyclonal antibody
产品名称： ADK polyclonal antibody
英文名称： ADK polyclonal antibody
产品编号： PAB4654
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of ADK.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human ADK.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
Immunohistochemistry (1:10-50)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Coupling of CFTR-mediated anion secretion to nucleoside transporters and adenosine homeostasis in Calu-3 cells.
Szkotak AJ, Ng AM, Man SF, Baldwin SA, Cass CE, Young JD, Duszyk M.J Membr Biol. 2003 Apr 1;192(3):169-79.
- 2.
- Gene structure for adenosine kinase in Chinese hamster and human: high-frequency mutants of CHO cells involve deletions of several introns and exons.
Singh B, Lin A, Wu ZC, Gupta RS.DNA Cell Biol. 2001 Jan;20(1):53-65.
- 3.
- Identification of a novel human adenylate kinase. cDNA cloning, expression analysis, chromosome localization and characterization of the recombinant protein.
Van Rompay AR, Johansson M, Karlsson A.Eur J Biochem. 1999 Apr;261(2):509-17.
- Applications
- Western Blot (Tissue lysate)
- Western blot analysis of ADK polyclonal antibody (Cat # PAB4654) in mouse liver tissue lysate (35 ug/lane). ADK (arrow) was detected using the purified polyclonal antibody (1 : 60 dilution).
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Formalin-fixed and paraffin-embedded human hepatocarcinomareacted with ADK polyclonal antibody (Cat # PAB4654), which was peroxidase-conjugated to the secondary antibody, followed by AEC staining.
This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
- Entrez GeneID:
- 132
- Protein Accession#:
- NP_006712
- Gene Name:
- ADK
- Gene Alias:
- AK
- Gene Description:
- adenosine kinase
- Omim ID:
- 102750
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes adenosine kinase, an abundant enzyme in mammalian tissues. The enzyme catalyzes the transfer of the gamma-phosphate from ATP to adenosine, thereby serving as a regulator of concentrations of both extracellular adenosine and intracellular adenine nucleotides. Adenosine has widespread effects on the cardiovascular, nervous, respiratory, and immune systems and inhibitors of the enzyme could play an important pharmacological role in increasing intravascular adenosine concentrations and acting as anti-inflammatory agents. Alternative splicing results in two transcript variants encoding different isoforms. Both isoforms of the enzyme phosphorylate adenosine with identical kinetics and both require Mg2+ for activity. [provided by RefSeq
- Other Designations:
- OTTHUMP00000019864,OTTHUMP00000019865,adenosine 5'-phosphotransferase
- Gene Pathway