分子量：Calculated MW: 36kDa/91kDa
Observed MW: 92kDa

细胞定位：Cell junction, Cell projection, Cytoplasm, axon, dendrite, dendritic spine, synapse

稀释方法：WB 1:500 - 1:2000

总结：This gene encodes a Rho-GTPase-activating protein that promotes GTP hydrolysis of Rho subfamily members. Rho proteins are important mediators of intracellular signal transduction, which affects cell migration and cell morphogenesis. Mutations in this gene are responsible for OPHN1-related X-linked mental retardation with cerebellar hypoplasia and distinctive facial dysmorhphism.