Phospho-p53-S376 Rabbit mAb (AMR11991N)
产品名称: Phospho-p53-S376 Rabbit mAb (AMR11991N)
英文名称: Phospho-p53-S376 Rabbit mAb (AMR11991N)
产品编号: AMR11991N
产品价格: null
产品产地: 美国
品牌商标: Leading Biology
更新时间: null
使用范围:
安诺伦(北京)生物科技有限公司
- 联系人 :
- 地址 : 北京大兴经济技术开发区天骥智谷35A
- 邮编 :
- 所在区域 : 北京
- 电话 : 189****2642 点击查看
- 传真 : 点击查看
- 邮箱 : 3359689365@qq.com
分子量:Calculated MW: 53kDa Observed MW: 53KDa 细胞定位:Cytoplasm, Endoplasmic reticulum, Mitochondrion matrix, Nucleus, PML body 稀释方法:WB 1:500 - 1:2000 总结:This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]