产品概述：Recombinant protein of human TAR DNA binding protein (TARDBP), full length, with C-terminal DDK tag, expressed in sf9 cells

蛋白长度：A DNA sequence from GoldORF clone, [GH40454V], encoding human full-length TARDBP

表达系统：Sf9

种属：Human

标签类型：C-DDK

分子量：45 kDa

通用名：TARDBP

总结：HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. [provided by RefSeq, Jul 2008]

形式：Liquid

浓度：>50 ug/mL as determined by microplate BCA method

纯度：> 80% as determined by SDS-PAGE and Coomassie blue staining

储存溶液：50mM Tris-HCl pH8.0, 150mM NaCl, 20% glycerol

别名：ALS10; TDP-43