分子量：Calculated MW: 14kDa/18kDa
Observed MW: 18KDa

细胞定位：Nucleus

稀释方法：WB 1:500 - 1:2000
IHC 1:50 - 1:200

总结：This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.