分子量：Calculated MW: 14kDa/17kDa/24kDa
Observed MW: 18kDa

细胞定位：Cytoplasm, Nucleus

稀释方法：WB 1:1000 - 1:2000
IHC 1:50 - 1:100
IF 1:50 - 1:200

总结：The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to participate in the ubiquitination of p53, c-Fos, and the NF-kB precursor p105 in vitro. Several alternatively spliced transcript variants have been found for this gene.