产品概述：Purified recombinant protein of human neurotrophic tyrosine kinase, receptor, type 3 (NTRK3), transcript variant 1, with C-terminal DDK/His tag, expressed in human cells, 20 g

蛋白长度：A DNA sequence from GoldORF clone, [GH69024V], encoding the region (Cys32-Thr429) of human NTRK3

表达系统：HEK293

种属：Human

标签类型：C-DDK/His

分子量：47 kDa

通用名：NTRK3

总结：This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011]

形式：Liquid

浓度：>50 ug/mL as determined by microplate BCA method

纯度：> 80% as determined by SDS-PAGE and Coomassie blue staining

储存溶液：PBS, pH7.4, 10% glycerol

别名：gp145(trkC); GP145-TrkC; TRKC