IDH2 Rabbit pAb (APR27184N)-抗体-抗体-生物在线
安诺伦(北京)生物科技有限公司
IDH2 Rabbit pAb (APR27184N)

IDH2 Rabbit pAb (APR27184N)

商家询价

产品名称: IDH2 Rabbit pAb (APR27184N)

英文名称: IDH2 Rabbit pAb (APR27184N)

产品编号: APR27184N

产品价格: null

产品产地: 美国

品牌商标: Leading Biology

更新时间: null

使用范围: WB (Mus musculus, Homo sapiens)

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分子量:Calculated MW: 45kDa/50kDa
Observed MW: 51kDa

细胞定位:Mitochondrion

稀释方法:WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:20 - 1:50
IP 1:50 - 1:200
ChIP 1:20 - 1:100

总结:Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. Alternative splicing results in multiple transcript variants.