产品概述：Purified recombinant protein of human CD86 molecule (CD86), transcript variant 1, with C-terminal DDK/His tag, expressed in human cells, 20 g

蛋白长度：A DNA sequence from GoldORF clone, [GH46837V], encoding the region (Leu20  Pro239) of human CD86

表达系统：HEK293

种属：Human

标签类型：C-DDK/His

分子量：27 kDa

通用名：CD86

总结：This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011]

形式：Liquid

浓度：>50 ug/mL as determined by microplate BCA method

纯度：> 80% as determined by SDS-PAGE and Coomassie blue staining

储存溶液：PBS, pH7.4, 10% glycerol

别名：B7-2; B7.2; B70; CD28LG2; LAB72